Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adversereactions reported.
The conversation discusses the positive effects of using Minoxidil and Finasteride for two years, with improvements in hair health and darkness noted. However, some side effects such as hair falling out easily and severe adversereactions were also mentioned.
A 35-year-old started finasteride in 2014 for hair loss and maintained hair density for 7 years, occasionally using ketoconazole shampoo. Switched to dutasteride in 2022 due to increased hair fall, experimented with dosages, and found a combination with tamsulosin effective despite initial adversereactions.
User experienced bad reaction to minoxidil and asks if anyone tried stemoxydine alone for hair loss. They consider trying stemoxydine with low dose topical finasteride after testing stemoxydine on a small area.
The conversation discusses the effectiveness of Exosomes as a hair loss treatment. A user recalls a doctor on Youtube showcasing successful results from using Exosomes.
A 24-year-old male has been using 0.5mg finasteride, 5% minoxidil twice daily, iron and zinc supplements, derma rolling weekly, and Nizoral weekly for hair loss. Despite these treatments, he experiences tight, painful scalp areas with no progress and some hair loss.
The conversation discusses why personal stories about hair loss treatments like Minoxidil and finasteride are often taken more seriously than scientific evidence in certain forums. People tend to believe what they want and use others' experiences to support their own views on treatment effectiveness and side effects.
A user is considering tapering off finasteride due to concerns about long-term side effects and cost, and is exploring alternatives like zinc and saw palmetto. Their current regimen includes finasteride, Adderall, zinc, bupropion, fish oil, baby aspirin, Rogaine foam, and ketoconazole shampoo.
Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.
A 33-year-old is using topical minoxidil, oral finasteride (1mg), a derma pen, and 0.05% tretinoin on the hairline to treat hair loss, showing progress after 2 months. They apply tretinoin in the evening with minoxidil and use a derma pen once a week at 1.5mm.
The conversation discusses a successful hair regrowth treatment involving topical Minoxidil (5%), 1 mg Finasteride, Microneedling, and Biotin + Vitamin D supplements. The user shares their routine and receives positive feedback on the significant progress made in just three months.
Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.
Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.
The user reported positive feedback on hair appearance after switching from topical to oral minoxidil and finasteride, with no side effects. The treatment includes 1.1mg finasteride, 3mg minoxidil, biotin, and vitamins B5, B6, and C daily.
The conversation is about the safety and effects of using pyrilutamide for hair loss. One person reported severe negative effects, another experienced minor side effects without much benefit for hair, and a third found the anecdote helpful in making a decision.
Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
A user experienced severe hair shedding and hairline recession after 10 months on finasteride. They are considering switching to dutasteride or adding minoxidil.
The user reports regrowth after 5 months using Minoxidil, finasteride, microneedling with a derma stamp, Nizoral shampoo, multivitamins, and biotin, and has shared progress pictures. They apply treatments daily, microneedle twice a week, and exercise regularly, noting an improvement in their mental well-being.
The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.
The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.
The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.
The conversation criticizes the negative attitude towards those concerned about side effects from hair loss treatments like finasteride and minoxidil, or who prefer natural remedies. Specific treatments discussed include finasteride, minoxidil, rosemary oil, and RU58841, with an agreement that finasteride and minoxidil are proven effective.
A user started taking 0.625mg oral minoxidil daily for hair loss, increased the dose to 1.25mg, and experienced a significant shed, losing 70% of scalp density. They cannot tolerate finasteride due to side effects but are hopeful for hair regrowth despite the shedding.
_the_orange_box_'s experience using oral minoxidil, with discussion about finasteride and the potential side effects of both treatments. Other users shared their own experiences related to hair loss treatments.
The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.
Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.
Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.
Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.
Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.
