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Glossary3D cell culture (Spheroid Culture)

technique growing cells in three dimensions for realistic conditions

3D cell culture is a technique used to grow cells in an environment that more closely mimics the natural conditions inside the human body compared to traditional two-dimensional (2D) cultures. By allowing cells to interact in all three dimensions, this method provides a more accurate representation of how cells behave, grow, and respond to treatments, making it particularly valuable for research in areas like cancer, tissue engineering, and drug development.

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community Surprisingly thorough study on He-Shou-Wu/Fo Ti

in Research/Science 14 upvotes 1 year ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community Developing a Cheap Low-Level Laser Therapy Device for Hair Loss

in Technology 6 upvotes 2 years ago

Low-level laser therapy (LLLT) stimulates hair growth but current devices are expensive. A proposed non-profit project aims to create affordable, 3D-printed LLLT devices and collect data on their effectiveness.

community Am I taking out too much foam for a dose? Rogaine Minoxidil

in Minoxidil 1 year ago

This conversation discusses the topical application of Minoxidil, with various users providing advice on how to accurately measure a dose and keep it from melting too quickly. Others have shared their experiences using oral finasteride for hair loss treatments.

community Scalp Micropigmentation while having hair

in Treatment 6 upvotes 2 years ago

User discusses scalp micropigmentation for denser hair appearance and its benefits compared to lifelong treatments. Special ink is used, which can fade and blur over time but can be topped up.

community Hair cloning- What is the current status and will it be available for the general population?

in Technology 7 upvotes 2 years ago

Hair cloning is discussed, focusing on its current status and potential availability. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community How soon is hair clone? Next five years?!

in Research/Science 15 upvotes 5 months ago

Hair cloning is humorously discussed as always being 5-7 years away, with skepticism about its near-term availability. Gene editing to reactivate dormant follicles is suggested as a more likely solution within the next ten years.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 9 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Red light therapy - research says they work, reviews say they don't - Turns out commercial device are severely under-powered, so could this actually work?

in Technology 74 upvotes 1 year ago

The conversation discusses the effectiveness of commercial Low-Level Laser Therapy (LLLT) devices for hair growth, suggesting they are underpowered compared to the ideal energy output shown in medical research. A user plans to build a custom helmet that meets the required specifications for effective treatment.

community Dermastamp only with carrier/essential oil blend

in Microneedling 15 upvotes 1 year ago

A user is documenting their natural approach to treating a receding hairline using a dermastamp, essential oils (rosemary oil at 3% dilution with pumpkin seed oil), a multivitamin with vitamin D, and daily collagen shakes. They acknowledge the common recommendations of minoxidil and finasteride but prefer to test natural methods and share their results.

community POV: Your hair is falling out.

in Treatment 2 years ago

Potential treatments for hair loss, including the use of minoxidil, finasteride, and RU58841.

community Oral minoxidil can causes age skin?

in Minoxidil 8 upvotes 2 years ago

Oral minoxidil may cause skin aging, such as dark circles. To counteract aging, use tretinoin at night and broad-spectrum sunscreen during the day.

community Success sttory – 22 to 27

in Progress Pictures 4 years ago

A user's success story of improving their hair loss with treatments that include finasteride, dutasteride, minoxidil, nizoral, and dermastamping; other products that have been tried with varying results; and potential side effects.

community L'Oreal working on Hair Cloning - Poster Presentation

in Research/Science 24 upvotes 4 years ago

L'Oreal is working on hair cloning, with multiple companies using similar techniques, making hair cloning likely by 2030. The conversation expresses optimism about the progress and potential affordability of hair cloning solutions.

community 3 years Fin/Om progress update

in Progress Pictures 364 upvotes 2 weeks ago

The user has been using finasteride since late 2021 and added oral minoxidil in mid-2024, considering adding dutasteride for better results. Users discuss the effectiveness and side effects of these treatments, with some recommending ketoconazole shampoo for redness.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 1 upvotes 2 weeks ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 411 upvotes 2 weeks ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community 2 months progress on minox 5% and .3% topical. Thoughts?

in Is this regrowth? 296 upvotes 4 months ago

User shared 2-month progress using 6% minoxidil, seeing some regrowth. Others encouraged consistency and noted significant results typically appear around months 3-6.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Why is it that low testosterone causes hair loss as well? How can I be balding?

in Chat 158 upvotes 8 months ago

The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

community 4 Months on 1mg Finasteride, 0.25mm Derma Roller with Rosemary Oil + Biotin Pills. 31 Years Old. (After & Before Pics)

in Progress Pictures 192 upvotes 11 months ago

A user shared progress pictures after 4 months of using 1mg finasteride, a 0.25mm derma roller with rosemary oil, and biotin pills for hair loss. They reported being very happy with the results.

community I just made my own PRP - DIY PRP

in Research/Science 548 upvotes 1 year ago

The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

community Hiding Baldness with Side Hair Growth

in Styling 145 upvotes 1 year ago

User hides baldness with side hair growth, others suggest it looks good but may not work in all conditions. Some recommend starting treatment or considering a hair transplant.

community HairCafe: The Broscience of Hair Loss, DHT, and Bludflow with Andrew Huberman

in Chat 1 year ago

Hair loss, DHT and bloodflow with Andrew Huberman; the discussion includes opinions about supplements, finasteride, minoxidil, turmeric, coffee and botox injections for hair loss.

community Hair Tattoo as a substitue to hair transplant

in Transplants 517 upvotes 1 year ago

A hair tattoo substitute for a hair transplant, which many people felt was not a good idea. Several treatments were suggested as alternatives, such as Scalp Micro Pigmentation (SMP) and wigs.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community Pumpkin seed oil tablet or topical oil.

in Treatment 9 upvotes 2 years ago

The conversation discusses the effectiveness of pumpkin seed oil for hair loss, with mixed opinions on its benefits. Some users mention studies showing potential hair growth benefits, while others consider it ineffective.

community 3 months on minoxidil and microneedling alone

in Progress Pictures 633 upvotes 2 years ago

This conversation was about a user's progress pictures from using minoxidil and microneedling to treat hair loss. Other users suggested finasteride as an additional treatment, while cautioning that the drug could have permanent side effects.

community DIY PRP Scalp Injections - wish me luck!

in Treatment 39 upvotes 4 years ago

A user shared their experience with DIY PRP scalp injections for hair regrowth, using an EZ Injector and other at-home equipment. Another user reported success with at-home PRP treatments for 1.5 years, noting thicker hair and a stable hairline.

community They said my hair would fall out and I wouldn’t keep my hair gains. 9 months on finasteride!

in Finasteride/Dutasteride 436 upvotes 4 years ago

A user's experience with finasteride to prevent hair loss, and how minoxidil may also have played a role in the successful results.

community Hair Cloning, Trials were supposed to begin 2020-2021

in Technology 48 upvotes 4 years ago

The conversation discusses hair cloning trials expected to start in 2020-2021 and mentions concerns about potential delays due to the Coronavirus. Treatments like Minoxidil, finasteride, and RU58841 are referenced.