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protein crucial for anchoring skin layers together

Collagen Type VII is a specific type of collagen protein that plays a crucial role in anchoring the outer layer of the skin (epidermis) to the underlying layer (dermis). It forms structures known as anchoring fibrils, which are essential for maintaining skin integrity and preventing blistering. Defects in Collagen Type VII can lead to a genetic condition called dystrophic epidermolysis bullosa, characterized by fragile skin that easily blisters and tears.

Related Terms

• COL7A1
• Recessive Dystrophic Epidermolysis Bullosa
• Anchoring Fibrils
• Dystrophic Epidermolysis Bullosa
• Type I Collagen
• Type III Collagen
• Collagen IV
• Collagen XVII