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    Glossary Collagen Type VII

    protein crucial for anchoring skin layers together

    Collagen Type VII is a specific type of collagen protein that plays a crucial role in anchoring the outer layer of the skin (epidermis) to the underlying layer (dermis). It forms structures known as anchoring fibrils, which are essential for maintaining skin integrity and preventing blistering. Defects in Collagen Type VII can lead to a genetic condition called dystrophic epidermolysis bullosa, characterized by fragile skin that easily blisters and tears.

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    Research 10 of 1000+

    1. [Effects of collagen type ⅩⅦ α1 on epidermal stem cells in aging skin and the microRNA intervention mechanism]. PubMed · 2022
    2. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    3. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    4. Identification of a human type XVII collagen fragment with high capacity for maintaining skin health Synthetic and systems biotechnology · 2024
    5. Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy Journal of Investigative Dermatology · 2013 · 27 citations
    6. Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation Tissue & Cell · 2019 · 11 citations
    7. Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa 2022 · 5 citations
    8. Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway Frontiers in Cell and Developmental Biology · 2026
    9. Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis 2017
    10. Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
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    Community 2 of 158

    1. Dr Kyle Gillett on topical Dutasteride Reddit · 21 Dec 2022
    2. Just got a dermastamp, and it is FAR superior to a roller. I’ll never go back. Reddit · 28 Feb 2024
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