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    Glossary Collagen Type VII

    protein crucial for anchoring skin layers together

    Collagen Type VII is a specific type of collagen protein that plays a crucial role in anchoring the outer layer of the skin (epidermis) to the underlying layer (dermis). It forms structures known as anchoring fibrils, which are essential for maintaining skin integrity and preventing blistering. Defects in Collagen Type VII can lead to a genetic condition called dystrophic epidermolysis bullosa, characterized by fragile skin that easily blisters and tears.

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    1. Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity Journal of Investigative Dermatology · 2000 · 42 citations
    2. Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells Journal of Dermatological Science · 2024 · 1 citations
    3. Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle. PubMed · 1992 · 45 citations
    4. Basement membrane Laminin and Type IV Collagen in Various Benign and Malignant Adnexal Tumors of the Skin: An Immunohistochemical Study Journal of Investigative Dermatology · 1984 · 28 citations
    5. Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway Frontiers in Cell and Developmental Biology · 2026
    6. Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C Advanced Science · 2025
    7. Effect of Hyaluronic Acid and Poly-L-Lactic Acid Dermal Fillers on Collagen Synthesis: An in vitro and in vivo Study Clinical, cosmetic and investigational dermatology · 2020 · 34 citations
    8. Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury Materials Today Bio · 2025
    9. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    10. Induction of follicle formation and hair growth by vibrissa dermal papillae implanted into rat ear wounds: vibrissa-type fibres are specified Development · 1992 · 125 citations
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