research [Factors related to collagen gel contraction in hair follicle organotypic culture].
Collagen gel contraction in hair follicle culture is mainly influenced by the amounts of collagen, dermal papilla cells, and epithelium cells.
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5 / 1000+ resultsresearch 376 Tsc2 disruption in mesenchymal progenitors regulates hair follicles and TGF beta signaling
This study in mice suggests that defects in hair follicles with mesenchymal TSC2 disruption may result from an impaired TGFβ1 response, indicating a potential novel treatment approach for tuberous sclerosis complex.
research Comparative Assessment of Topical Platelet-Rich Plasma and Phenytoin for Diabetic Foot Ulcer Healing in a Rat Model
In this study, both platelet-rich plasma gel and 1% phenytoin cream showed comparable results for wound healing in diabetic foot ulcers in rats, with PRP providing slightly advanced histological improvements; however, the differences were not statistically significant.
research Reconstruction of Tissue Engineered Skin Substitute Containing Appendages Using Dermal Papillae Cells And Keratinocytes
This study found that incorporating dermal papillae cells and keratinocytes into dermal substitutes promoted better wound healing, reduced contraction, and enabled appendage formation in tissue-engineered skin on mice.
research EVALUATION OF CRUDE FLAXSEED (Linum usitatissimum L.) OIL IN BURN WOUND HEALING IN NEW ZEALAND RABBITS
This study found that linseed oil, rich in flavonoids and terpenoids, significantly improved burn wound healing in terms of faster contraction, reduced inflammation, and enhanced tissue regeneration compared to other treatments, without adverse effects.
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5 / 1000+ resultscommunity Deoxyribose Gel? Does it work ?
The conversation discusses the use of Medicube Deoxyribose Gel for hair loss, with skepticism about its effectiveness due to lack of human trials. The original poster uses a combination of minoxidil, finasteride, dutasteride, RU58841, GHK-CU, and is considering adding deoxyribose gel and ketoconazole.
community Will minoxidil cause your skin to age from the collagen inhibition?
Minoxidil is unlikely to cause skin aging at typical doses, and concerns about collagen inhibition are mostly unfounded. Users suggest using sunscreen and tretinoin for skin health, and some combine minoxidil with finasteride for hair maintenance.
community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?
Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.
community Is this true? It can be a major breakthrough
Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.
community Does anyone have experience with topical dut?
The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.
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