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GlossaryTranscription Co-activator (Co-activator)

protein that helps activate gene expression by binding to transcription factors

A transcription co-activator is a protein that helps turn on the expression of specific genes by binding to transcription factors, which are proteins that directly interact with DNA. While co-activators do not bind to DNA themselves, they facilitate the assembly of the transcription machinery, enhancing the efficiency of gene transcription. This process is crucial for regulating various biological functions, including hair growth and the response to conditions like alopecia.

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research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor

December 2016 in “Springer eBooks”

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

research Androgen Actions on the Human Hair Follicle: Perspectives

115 citations , September 2012 in “Experimental Dermatology”

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

research Androgens and Androgen Receptor Action in Skin and Hair Follicles

100 citations , September 2017 in “Molecular and Cellular Endocrinology”

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

research Many Paths to Alopecia via Compromised Regeneration of Hair Follicle Stem Cells

8 citations , May 2013 in “Journal of Investigative Dermatology”

Different problems with hair stem cell renewal can lead to hair loss.

research Vitamin D and the Skin: Physiology and Pathophysiology

158 citations , August 2011 in “Reviews in endocrine and metabolic disorders”

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.