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GlossaryKeratin 1 (CK1)

protein providing structural support in skin cells

Keratin 1 (KRT1) is a type of protein found in the outer layer of the skin, playing a crucial role in providing structural integrity and resilience. It partners with Keratin 10 to form intermediate filaments, which help skin cells withstand mechanical stress and prevent damage. Mutations in the KRT1 gene can lead to skin disorders such as epidermolytic hyperkeratosis, characterized by blistering and thickened skin.

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research Cytokeratin 15 Expression in Central, Centrifugal, Cicatricial Alopecia: New Observations in Normal and Diseased Hair Follicles

14 citations, January 2011 in “Journal of Cutaneous Pathology”

CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.

research The Localization of Cytokeratin 19 and Vimentin in Sprague Dawley Albino Rat Skin Tissue

1 citations, March 2014 in “Applied Microscopy”

CK19 and Vimentin are proteins found in rat skin that help with skin renewal and maintaining cell structure.

research Epidermal Stem Cells: Practical Perspectives and Potential Uses

62 citations, April 2009 in “British Journal of Dermatology”

Epidermal stem cells could lead to new treatments for skin and hair disorders.

research Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia

54 citations, January 2009 in “British Journal of Dermatology”

Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.

research Hair Follicle Stem Cells in the Pathogenesis of the Scarring Process in Cutaneous Lupus Erythematosus

31 citations, January 2009 in “Autoimmunity Reviews”

Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.

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community Pyrilutamide update number 2 - 2 week use

in Update 174 upvotes 2 years ago

An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.