1 citations
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July 2022 in “Journal of dermatology” This study found that in vivo and in vitro, citric acid metabolism through the CS-CA axis suppressed hair growth and induced inflammation and cell apoptosis in hair follicles, suggesting it as a potential therapeutic target.
January 2023 in “International journal of biological sciences” This study found that ATP synthases and the mitochondrial gene COX2 play a key role in determining the size of skin appendages in hedgehogs and mice by influencing energy metabolism and cell proliferation.
30 citations
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October 2015 in “Journal of Ethnopharmacology” This study identified several compounds from traditional Chinese medicines that may inhibit prostaglandin D2 synthase, potentially providing promising candidates for treating androgenic alopecia with minimal adverse skin reactions.
14 citations
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June 2015 in “Toxicology and Industrial Health” This study found that low doses of bisphenol A may increase proliferation of the ventral prostate in adult rats by altering the estrogen to androgen ratio and gene expression.
20 citations
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March 2013 in “Journal of Lipid Research” This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.