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GlossaryCircular RNAs

circular RNA molecules form closed loops, enhancing stability

Circular RNAs (circRNAs) are a type of RNA molecule that, unlike the more common linear RNAs, form a covalently closed loop. This unique structure makes them more stable and resistant to degradation. They play various roles in gene regulation, including acting as molecular sponges for microRNAs, and are being studied for their potential involvement in diseases and as therapeutic targets.

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The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

research The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

3 citations, February 2022 in “Frontiers in cell and developmental biology”

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

research The Role of MicroRNA, Long Non-Coding RNA, and Circular RNA in the Pathogenesis of Polycystic Ovary Syndrome: A Literature Review

1 citations, January 2024 in “International journal of molecular sciences”

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

research Comprehensive Analysis of the Circular RNA Expression Profile and CircRNA–miRNA–mRNA Network in the Goat Skin with Divergent Wool Curvature

December 2023 in “Animal research and one health”

Certain circular RNAs are crucial for wool growth and curvature in goats.

research The Circular RNA circNlgn Mediates Doxorubicin-Induced Cardiac Remodeling and Fibrosis

19 citations, June 2022 in “Molecular therapy. Nucleic acids”

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

research Detection of Circular RNA Expression and Related Quantitative Trait Loci in the Human Dorsolateral Prefrontal Cortex

48 citations, May 2019 in “Genome Biology”

Researchers found that certain RNA circles in the brain are linked to disease risk, but their exact role in disease is still unknown.

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community Microneedling technique clarification

in Microneedling 16 upvotes 4 months ago

The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.

community 8 months into the journey. I didn’t think I’d ever have hair again.

in Progress Pictures 260 upvotes 7 months ago

The user regained hair using a routine including Nizoral shampoo, 0.5mg finasteride daily, topical minoxidil at night, and microneedling every two weeks. They switched from topical to oral finasteride to save money.

community 1 year progress | 1mg fin daily and topical min twice daily

in Progress Pictures 363 upvotes 1 year ago

A user's 1 year progress of using finasteride daily and minoxidil twice daily to treat hair loss, with other users congratulating him on the significant improvement.

community Finasteride is love, Finasteride is life

in Finasteride/Dutasteride 35 upvotes 2 years ago

The positive effects of taking finasteride for hair loss, with the poster being four months into treatment and seeing improved thickness on their right side of scalp. Another user replied expressing hope in having similar results after starting to take finasteride.

community 7 months fin, 10 months min, 4 months dut. Should I continue?

in Is this regrowth? 161 upvotes 5 months ago

The user has been using finasteride for 7 months, minoxidil for 10 months, and dutasteride for 4 months with minimal results and is considering stopping treatment. Replies suggest continuing treatment, adding microneedling, and checking DHT levels.

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