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GlossaryCircular RNAs

circular RNA molecules form closed loops, enhancing stability

Circular RNAs (circRNAs) are a type of RNA molecule that, unlike the more common linear RNAs, form a covalently closed loop. This unique structure makes them more stable and resistant to degradation. They play various roles in gene regulation, including acting as molecular sponges for microRNAs, and are being studied for their potential involvement in diseases and as therapeutic targets.

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The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

research The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

3 citations , February 2022 in “Frontiers in cell and developmental biology”

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

research Comprehensive Analysis of the Circular RNA Expression Profile and CircRNA–miRNA–mRNA Network in the Goat Skin with Divergent Wool Curvature

December 2023 in “Animal research and one health”

Certain circular RNAs are crucial for wool growth and curvature in goats.

research The Role of MicroRNA, Long Non-Coding RNA, and Circular RNA in the Pathogenesis of Polycystic Ovary Syndrome: A Literature Review

1 citations , January 2024 in “International journal of molecular sciences”

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

research CircERCC6 Positively Regulates the Induced Activation of SHF Stem Cells in Cashmere Goats via the miR-412-3p/BNC2 Axis in an m6A-Dependent Manner

January 2024 in “Animals”

Circular RNA ERCC6 helps activate stem cells important for cashmere goat hair growth by interacting with specific molecules in an m6A modification-dependent way.

Novel circRNAs From Cashmere Goats: Discovery, Integrated Regulatory Network, and Their Putative Roles in the Regeneration and Growth of Secondary Hair Follicles

research Novel circRNAs From Cashmere Goats: Discovery, Integrated Regulatory Network, and Their Putative Roles in the Regeneration and Growth of Secondary Hair Follicles

7 citations , June 2022 in “Czech Journal of Animal Science”

Certain circular RNAs help cashmere goats grow more hair.

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community What hair loss pattern is this?

KyleButler in General 157 upvotes 3 months ago

The user noticed small circular hairless spots after a buzz cut and has been using finasteride, dutasteride, and oral minoxidil for hair loss. They are experiencing continuous shedding and thinning, and it is suggested they consult a dermatologist for a scalp examination and possible biopsy to determine if it's alopecia areata or androgenetic alopecia.

community Microneedling technique clarification

in Microneedling 16 upvotes 1 year ago

The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.

community 1 year progress | 1mg fin daily and topical min twice daily

in Progress Pictures 363 upvotes 3 years ago

A user's 1 year progress of using finasteride daily and minoxidil twice daily to treat hair loss, with other users congratulating him on the significant improvement.

community 5 months on Minoxidil + 1mg Fin + Consistent Scalp Massage

in Progress Pictures 15 upvotes 1 month ago

Using minoxidil, finasteride, and consistent scalp massage improved hair growth. Adding pepper and garlic daily also contributed to better results.

community Finasteride is love, Finasteride is life

in Finasteride/Dutasteride 35 upvotes 3 years ago

The positive effects of taking finasteride for hair loss, with the poster being four months into treatment and seeing improved thickness on their right side of scalp. Another user replied expressing hope in having similar results after starting to take finasteride.

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