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Glossary Cimetidine

medication reduces stomach acid and may treat certain hair loss

Cimetidine, also known by the brand name Tagamet, is a medication primarily used to treat conditions like ulcers, gastroesophageal reflux disease (GERD), and other issues caused by excess stomach acid. It works by blocking histamine H2 receptors in the stomach lining, thereby reducing acid production. Interestingly, cimetidine has also been explored for off-label uses, such as treating certain types of hair loss (alopecia) due to its potential immune-modulating effects.

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Research

5 / 330 results

research Treatment of Female Androgenetic Alopecia With Cimetidine

19 citations , March 1987 in “International Journal of Dermatology”

This study reports that cimetidine treatment resulted in good to excellent hair regrowth in 70% of the small group of women with androgenetic alopecia, with no major side effects observed.

research Treatment of hirsutism with cimetidine: a prospective randomized controlled trial

17 citations , February 1989 in “Fertility and sterility”

In this study, cimetidine at a daily dose of 1.5 gm for 3 months did not significantly affect hair growth in women with moderate to severe hirsutism.

research Hormonal changes and hair growth during treatment of hirsutism with cimetidine.

2 citations , January 1984 in “PubMed”

This study concluded that cimetidine did not significantly affect hair growth in women with hirsutism, despite a notable decrease in urine 17-ketosteroids.

research Formulation and Evaluation of Cimetidine as a Topical Preparation

1 citations , June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences”

This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.

research Treatment of Female Androgenic Alopecia with Cimetidine

September 1987 in “International Journal of Dermatology”

Cimetidine is not a first-choice treatment for female hair loss, and there's no consistently successful treatment for this condition in men or normal hormone level women.

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learn Cetirizine

popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

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community topical cetirizine to control scalp inflammation

4 upvotes 4 years ago

The user applies a topical solution containing minoxidil, finasteride, dutasteride, retinoic acid, and hydrocortisone to address scalp inflammation and is considering adding cetirizine to the mix. They are calculating the correct amount of cetirizine to add to their formula and have paused this approach to retry oral minoxidil.

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