19 citations
,
March 1987 in “International Journal of Dermatology” This study reports that cimetidine treatment resulted in good to excellent hair regrowth in 70% of the small group of women with androgenetic alopecia, with no major side effects observed.
17 citations
,
February 1989 in “Fertility and sterility” In this study, cimetidine at a daily dose of 1.5 gm for 3 months did not significantly affect hair growth in women with moderate to severe hirsutism.
2 citations
,
January 1984 in “PubMed” This study concluded that cimetidine did not significantly affect hair growth in women with hirsutism, despite a notable decrease in urine 17-ketosteroids.
1 citations
,
June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” This study found that a cimetidine 10% cream with sodium lauryl sulphate significantly increased drug diffusion through mouse skin and showed promise in treating warts in a preliminary clinical trial.
September 1987 in “International Journal of Dermatology” Cimetidine is not a first-choice treatment for female hair loss, and there's no consistently successful treatment for this condition in men or normal hormone level women.
81 citations
,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” This review discusses the classifications, diagnostic methods, and treatment strategies for female pattern hair loss, but reports no clinical results.
33 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.
32 citations
,
November 1996 in “International Journal of Dermatology” This review discusses the use of antiandrogen therapy in dermatology, covering treatments for conditions like acne, hirsutism, and androgenic alopecia but reports no new clinical findings.
22 citations
,
March 2000 in “Clinics in Dermatology” This study developed a method using HPLC with UV-DAD and ESI-MS detection to identify prohibited substances like minoxidil and hormones in cosmetic products advertised online for hair loss and skin conditions.
20 citations
,
September 1995 in “PubMed” This review discusses the wide range of drugs potentially causing reversible or irreversible hair loss and emphasizes the difficulty of diagnosing drug-induced alopecia without withdrawal of the suspected medication; it reports no new clinical findings.
19 citations
,
January 1997 in “Dermatologic Clinics” This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.
11 citations
,
January 1998 in “Dermatology” This review explores various substances with potential antiandrogenic effects for treating acne, highlighting evidence for isotretinoin, and discusses the future consideration of 5 alpha-reductase inhibitors as antiandrogens.
2 citations
,
September 1987 in “International Journal of Dermatology” Minoxidil caused hair to grow in unintended areas, like a tail, in a young girl.
March 2023 in “Zdorov'â čolovìka” This article reviews how various medications, such as antihypertensives, chemotherapy, and hormonal contraceptives, are associated with negative effects on sexual desire and function but reports no new clinical results.
January 2005 in “Farmaceutski glasnik” This review discusses various substances used in the treatment of alopecia, highlighting the roles of minoxidil and finasteride, but reports no new experimental findings.
July 1988 in “Journal of The American Academy of Dermatology” This article reviews therapeutic advances published between December 1986 and December 1987 but reports no new research findings; readers are advised to consult the original articles before considering new therapies.
6 citations
,
November 1990 in “DICP” This study found that rapidly administered intravenous cimetidine may cause a significant drop in blood pressure in critically ill patients, whereas ranitidine does not appear to have the same effect.
January 2026 in “International Journal of Unani and Integrative Medicine” This study evaluated the antiulcer potential of Glycyrrhiza glabra and found that its hydroalcoholic extract demonstrated dose-dependent protective effects against various ulcer models, comparable to standard drugs like omeprazole and cimetidine, by enhancing mucosal defenses and reducing stomach acid production.
1 citations
,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” This review discusses the roles of hair follicles and sebaceous glands in percutaneous transport and reports no new results, noting a lack of adequate models and methodologies.
October 2015 in “药物不良反应杂志” This review describes drug-induced gynecomastia, which results from an imbalance between estrogen and androgen action, listing potential treatments but no new clinical results.
February 1990 in “Journal of The American Academy of Dermatology” This review summarizes therapeutic advances reported in English-language literature from December 1987 to December 1988 and states no new clinical results.
January 1978 in “Clin-Alert” A document listed serious side effects from various drugs, including deaths and diseases, emphasizing the importance of being aware of drug side effects.
August 2026 in “Pakistan Journal of Pharmaceutical Sciences” In rats with cyclophosphamide-induced hair loss, this study found that applying cetirizine HCl-loaded emulgel with microneedling stimulated hair growth, suggesting a potentially safer alternative to minoxidil for treating chemotherapy-induced alopecia.
September 2024 in “Revista Científica de Salud BIOSANA” This systematic review explored the potential of cetirizine, an anti-inflammatory antihistamine, as a complementary treatment for androgenetic alopecia, reporting that it might help prevent hair follicle miniaturization by reducing inflammation and modulating immune activity, without notable side effects.
January 2016 in “Elsevier eBooks” Finasteride helps hair growth.
August 2026 in “Journal of Research in Pharmacy Practice” In this single-blind clinical trial, adding 1% topical cetirizine to 5% topical minoxidil for 16 weeks did not show improved hair growth outcomes in patients with androgenetic alopecia compared to minoxidil alone, although patient satisfaction was higher with the addition of cetirizine.
January 2025 in “Organics” This study found that differently charged micelles influence the acid-base equilibria of cetirizine by altering its ionization constants, indicating potential interactions with biomolecules of various charges under physiological conditions.
May 2026 in “Bioorganic Chemistry”
14 citations
,
January 2020 in “International Journal of Biological Sciences” This study found that ranitidine and finasteride may have cardiovascular and renal protective effects in mice by inhibiting TMAO synthesis and improving gut microbiota composition.
21 citations
,
June 2017 in “Journal of Dermatological Treatment” This study found that topical cetirizine 1% significantly improved hair density and diameter in patients with androgenetic alopecia, with patients tolerating the treatment well.