Scalp biopsies are crucial for diagnosing hairloss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hairloss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
Bryan Johnson uses a custom hairloss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.
A user has been treating hairloss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hairloss, and they are considering other treatments or causes.
In this conversation, 4990 discussed various treatments for hairloss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.
A user is concerned that finasteride isn't working for their hairloss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.