December 2025 in “Molecular Pain” This study identified that the MC-5-HT-HTR2A axis plays a role in chronic pruritus in a mouse model of SADBE-induced allergic contact dermatitis, suggesting potential for therapeutic targeting.
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October 2019 This study found that skin-infiltrating neutrophils play a crucial role in triggering chronic itch in atopic dermatitis by promoting skin hyperinnervation and enhanced expression of itch signaling molecules in a mouse model.
This study found that neutrophils are crucial for initiating chronic itch in atopic dermatitis and suggest that targeting neutrophils may help alleviate symptoms in this condition.
2 citations
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September 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” This study reported that AutoML effectively modeled itching and pain development, as well as app use, in patients with chronic eczema or psoriasis using a smartphone monitoring app, revealing that factors like BMI, age, and disease activity significantly influenced app engagement.
January 2026 in “Journal of Biosciences and Medicines” This research highlights the common and varied skin-related symptoms associated with chronic kidney disease, emphasizing that early recognition and multi-pronged management involving nephrology and dermatology can improve patient outcomes.