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This study analyzed post-marketing data from the U.S. FDA Adverse Event Reporting System and identified both known and new safety concerns for Avacopan, an anti-neutrophil cytoplasmic antibodies-associated vasculitis treatment, emphasizing the need for monitoring during early treatment stages.

This case report documents a rare instance of Rapunzel syndrome causing biliary obstruction in a 3-year-old girl, highlighting the importance of considering trichobezoar in cholestasis diagnosis.

In this case report and literature review, researchers identified a novel mutation in the CLDN1 gene linked to neonatal ichthyosis-sclerosing cholangitis syndrome and found that its phenotype varies widely, suggesting a multidisciplinary approach is crucial for management.

This review discusses skin changes and dermatoses during pregnancy and reports no clinical findings, emphasizing a need for better understanding of their causes.

This study found that polymorphic eruption was the most common pregnancy-related dermatosis, occurring mostly in the third trimester.