19 citations
,
January 2019 in “Ginekologia Polska” This study found that combined Myo-inositol and D-chiro-inositol therapy improved metabolic and hormonal parameters, including weight, hormone levels, and skin conditions, in women with PCOS after 6 months.
11 citations
,
January 2024 in “Gynecological Endocrinology” This narrative review on inositol use in PCOS treatment found positive results for myo-inositol alone and effective outcomes for a myo-inositol/D-chiro inositol combination at a 40:1 ratio, suggesting further research on other combinations like 66:1 to 100:1.
1 citations
,
January 2022 This study reported that a combination of Myo-inositol and D-chiro-Inositol improved clinical and laboratory parameters in teenage girls with PCOS compared to a placebo.
October 2025 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that Myoinositol and D-chiro inositol treatment improved fertility outcomes in women with PCOS, particularly in Phenotypes A and D, but larger studies are needed to confirm these results.
This review summarizes evidence suggesting that the ratio of Myo-Inositol to D-Chiro-Inositol in follicular fluid is crucial for oocyte and embryo quality.