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research Lineage-Committed Fibroblast Populations Are More Efficient at Regenerating Hair Follicles in Chamber Grafting Assays Compared to Undifferentiated Embryonic Fibroblasts

April 2018 in “Journal of Investigative Dermatology”

Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.

research Lineage Commitment of Dermal Fibroblast Progenitors Is Mediated by Chromatin De-repression

1 citations, March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

research Conditioned Media Obtained from Human Outer Root Sheath Follicular Keratinocyte Culture Activates Signalling Pathways That Contribute to Maintenance of Hair-Inducing Capacity and Increases Trichogenicity of Cultured Dermal Cells

6 citations, July 2012 in “Experimental Dermatology”

The substance from human hair root cells can help maintain hair growth and make skin cells more capable of growing hair.

Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia

research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia

69 citations, August 1999 in “Developmental biology”

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

research Dermal Fibroblast Expression of LEF1 Is Critical to Normal Skin and Hair Development and Regenerative Wound Healing in Mice

July 2022 in “Journal of Investigative Dermatology”

Lef1 is essential for normal skin, hair growth, and healing wounds in mice.

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community [20M] Hair Regrowth with Minoxidil ONLY- Need Opinions

in Minoxidil 244 upvotes 7 months ago

A 20-year-old is using minoxidil for hair regrowth and considering finasteride despite concerns about side effects. Many suggest adding finasteride to maintain gains, with recommendations to start with a low dose or use a topical form to minimize side effects.

community Why is the hype for oral minoxidil recent? It’s been around for 50 years.

in Minoxidil 76 upvotes 2 weeks ago

Oral minoxidil is gaining popularity due to increased awareness and convenience, despite potential side effects like cardiac issues and unwanted hair growth. Users report mixed results, with some seeing significant regrowth and others experiencing side effects or minimal improvement.

community New hair institute, Seoul, Dr Ko - 2000 graft no shave fue

in Transplants 55 upvotes 2 months ago

A user shared their positive experience with a no shave FUE hair transplant by Dr. Ko in Seoul, including aftercare with oxygen therapy, red light therapy, and prescribed dutasteride and oral minoxidil (2.5mg daily). The procedure cost over $5,000 USD, and the user is satisfied with the results.

community What makes them say exercise doesn't increase hair loss?

in Research/Science 45 upvotes 7 months ago

Exercise has minimal impact on hair loss, with weight lifting slightly increasing DHT and cardio potentially decreasing it. Finasteride and dutasteride are effective treatments for managing hair loss, even for those who exercise regularly.

community Dht test results after 1year oral dut

in Treatment 12 upvotes 1 year ago

The user is experiencing increased hair shedding after one year of using oral dutasteride. They are seeking opinions on their DHT test results, which show levels below baseline.

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