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    GlossaryCellular Retinoic Acid-Binding Protein 2

    protein that regulates retinoic acid's effects in cells

    Cellular Retinoic Acid-Binding Protein 2 (CRABP2) is a protein that binds to retinoic acid, a derivative of vitamin A, and helps regulate its availability and activity within cells. This protein plays a crucial role in cell growth, differentiation, and apoptosis, making it important in processes like skin health and hair growth.

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      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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      learn Adenosine

      nucleoside used for hair regrowth stimulant properties

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 6 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      by noeyys in Research/Science  62 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      by asyntheticpug in Research/Science  732 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
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      community Just found out I am Vitamin D deficient

      by throwawayyougetme in Treatment  58 upvotes 3 years ago
      A user found out they are vitamin D deficient and was prescribed high-dose vitamin D supplements, asking if others had similar experiences and if it improved their hair. Some shared improved mood and testosterone levels after treatment, while another combined vitamin D supplements with finasteride due to family history of baldness.

      community What's the deal with verteporfin?

      by amrdxx in Research/Science  23 upvotes 1 year ago
      The conversation discusses verteporfin as a potential hair loss treatment and questions why more precise methods aren't used to test its effectiveness in regrowing hair. Some users believe verteporfin is promising and should receive more attention, while others are skeptical about the testing methods.