In Arabidopsis thaliana, this study found that proper O-glycosylation of extensins is crucial for root hair elongation and self-assembly of the cellwall.
109 citations
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February 2018 in “CB/Current biology”
This study concluded that the receptor-like kinase ERULUS, regulated by auxin, is crucial for modulating cellwall composition and pectin dynamics during root hair growth in Arabidopsis.
33 citations
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February 2016 in “Journal of Experimental Botany”
This study found that the receptor kinase RHS10 negatively regulates root hair growth in Arabidopsis thaliana by modulating growth duration and is associated with cellwall signal mediation, involving RNA catabolism and ROS accumulation.
In this review, the researchers discussed the role of cellwall components and proteins in root hair growth, emphasizing the complex interplay of subcellular factors, and identified open questions and future research directions in root hair mechanobiology.
2 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cellwall components, which is crucial for hardening the root hair shank in Arabidopsis.
MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.
The conversation is about the role of vitamin deficiencies in hair loss and the effectiveness of treatments like Minoxidil, finasteride, and RU58841. It concludes that while vitamins and nutrition are important, they are not the primary solution for androgenic alopecia.
Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.
A user diagnosed with lymphoma is advised to stop finasteride during chemotherapy, with suggestions to consider treatments like Dutasteride and Minoxidil post-recovery. The focus is on prioritizing health over hair loss, with encouragement and advice from others who have experienced similar situations.
Researchers at the University of Virginia discovered a new group of stem cells in hair follicles that could potentially restore hair growth. The findings suggest that activating these stem cells might offer a new way to combat hair loss, though practical treatments are still years away.