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research Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling

5 citations , May 2021 in “EMBO journal”

This review discusses the role of polarity signaling in coordinating tissue mechanics, micro-environmental functions, and cell fate decisions, but it reports no new results, highlighting the need for further study in mammalian models.

Epigenetic Orchestration of RNA m6A Methylation in Wound Healing and Post-Wound Events

research Epigenetic orchestration of RNA m⁶A methylation in wound healing and post-wound events

3 citations , July 2025 in “International Journal of Biological Sciences”

This review highlights that the RNA modification N⁶-methyladenosine (m⁶A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.

research Establishing an academic laboratory: mentoring as a business model

1 citations , October 2014 in “Molecular Biology of the Cell”

This essay discusses the author's views on establishing a successful academic laboratory and reports no new research findings.

research Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis

2 citations , June 2026 in “Frontiers in Science”

This review examines the potential of regulatory T cell-based therapies to transform treatment across various medical specialties by promoting immune tolerance and tissue repair, but it reports no new clinical results.

Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration

research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration

19 citations , April 2015 in “Stem Cells”

This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.

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Learn

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learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor promotes hair growth by signaling cell survival and division.
How does stem cell factor help activate dormant hair follicles? Stem cell factor activates dormant hair follicles by signaling through the c-Kit receptor.
Are stem cell factor products safe for long-term scalp use? Stem cell factor products lack proven long-term safety for scalp use.
All 5 questions on Stem Cell Factor →

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Beta Polypeptide

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Community Join

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community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

13 upvotes 1 year ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

140 upvotes 11 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Cell senescence-targeted treatment for hair loss, has anyone tried any products/enzymes etc. that use this theory

5 upvotes 1 year ago

DHT causes hair loss by driving cells into senescence, and a polyphenol in black chokeberry may reverse this. A product using this theory is being considered for use alongside finasteride, minoxidil, and microneedling.

community Has anyone here actually undergone experimental (grey market) hair cell therapy/follicle cloning?

7 upvotes 5 months ago

Hair cell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.

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Clinics

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