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research Interactive analysis of single-cell trajectories in 3D space with Cell Journey

1 citations , January 2026 in “GigaScience”

This study introduces Cell Journey, a new platform for visualizing RNA velocity in 3D, which aims to better capture complex cellular transitions in single-cell datasets compared to current 2D methods.

research O21 Single-cell RNA sequencing and proteomic analysis of dermal fibroblasts cultured from female scalp identifies significant alterations in cell populations with age

July 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

This study investigated age-related changes in female scalp dermal fibroblasts, finding alterations in gene and protein expressions associated with fibrosis and senescence, which could potentially affect hair follicle health and contribute to aging-related hair changes.

research Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata

4 citations , July 2025 in “Frontiers in Immunology”

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

research Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease

4 citations , June 2025 in “Cell Reports”

In this study using the C3H/HeJ mouse model of alopecia areata, researchers found that hyperexpanded CD8⁺ T cell clones were sufficient to initiate disease, establishing a causal link between T cell clonality and pathogenicity.

research Three-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon Microscopy

31 citations , September 2016 in “PLoS ONE”

The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.

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Community Join

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community Anyone Try Microneedling with Exosomes/AAPE?

2 upvotes 4 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community Most promising cures for baldness as of May 2026

70 upvotes 4 months ago

PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

community Another molecular pathway to promote scarless healing and regenerate hair follicles

14 upvotes 8 months ago

Carnosic acid in rosemary extract may enhance skin repair and promote hair follicle regeneration. It could be used alone or with verteporfin for scarless healing after dermal wounding.

community Possible transgenerational effects of finasteride use on male offspring? (STUDY)

in Research/Science 27 upvotes 4 months ago

Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.

community Is this true? It can be a major breakthrough

1008 upvotes 5 months ago

Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.

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Learn

4 / 800 results

learn Platelet-Rich Plasma

Concentrate of your own blood platelets, injected into the scalp

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor is a signalling protein linked to hair colour in lab and mouse studies; it is not a proven hair-loss treatment in people.
Does stem cell factor help activate dormant hair follicles? Lab and mouse studies link stem cell factor to hair colour; it has not been shown to reactivate dormant hair follicles in people.
Are stem cell factor products safe for long-term scalp use? Long-term safety of stem cell factor scalp products has not been studied in people; the one human trial of injected stem cell factor reported skin reactions and lasting dark patches.
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learn Apple stem cell

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Clinics

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