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SRD5A3

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research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

260 citations , July 2010 in “Cell”

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

research Alginate-Based Hydrogel Containing Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex for Topical Alopecia Treatment

19 citations , November 2017 in “Journal of Pharmaceutical Sciences”

A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.

research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates

21 citations , January 2020 in “General and Comparative Endocrinology”

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

research ATP6AP1-CDG: Follow-Up and Female Phenotype

7 citations , April 2020 in “JIMD Reports”

ATP6AP1‐CDG can cause hearing loss, hair loss, and protein issues, even in female carriers.

Characterization of Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex in Aqueous Alginate Gel Useful for Alopecia Management: Efficacy Evaluation in Male Rats

research Characterization of Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex in Aqueous Alginate Gel Useful for Alopecia Management: Efficacy Evaluation in Male Rats

19 citations , October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics”

The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.

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community Transitioning from fin to RU58841 + Oral Minoxidil - how long until I lose all my fin gains?

in Update 3 upvotes 7 months ago

The user transitioned from finasteride to RU58841 and oral minoxidil to maintain hair gains while avoiding systemic DHT suppression. They have not experienced increased shedding or side effects since stopping finasteride and hope RU58841 will preserve their hair.

community My Finasteride Story (Pictures + Blood work + Updates)

in Finasteride 11 upvotes 7 years ago

A user shared their experience with finasteride for hair regrowth, which was effective but caused side effects like gynecomastia and mood swings. They now manage side effects with Arimidex and vitamins while continuing finasteride, and monitor their health with blood tests.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 2 years ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.