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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A new gel containing minoxidil can treat hair loss effectively, potentially reducing side effects and improving treatment.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Drug repurposing shows promise for treating many medical conditions.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.

New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.

The new adhesive nanoparticles are effective for delivering Minoxidil to the scalp without skin irritation.