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SRD5A3

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SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

260 citations , July 2010 in “Cell”

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

research Drug Repurposing Patent Applications April–June 2021

September 2021 in “Assay and drug development technologies”

Drug repurposing shows promise for treating many medical conditions.

research Adverse Effects of 5α-Reductase Inhibitors: What Do We Know, Don't Know, and Need to Know?

111 citations , August 2015 in “Reviews in Endocrine and Metabolic Disorders”

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

How to Diagnose a Lipodystrophy Syndrome

research How to Diagnose a Lipodystrophy Syndrome

53 citations , June 2012 in “Annales d'Endocrinologie”

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

research Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

9 citations , August 2021 in “Journal of clinical medicine”

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

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community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 2 years ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

community My Finasteride Story (Pictures + Blood work + Updates)

in Finasteride 9 upvotes 7 years ago

A user shared their experience with finasteride for hair regrowth, which was effective but caused side effects like gynecomastia and mood swings. They now manage side effects with Arimidex and vitamins while continuing finasteride, and monitor their health with blood tests.

community Transitioning from fin to RU58841 + Oral Minoxidil - how long until I lose all my fin gains?

in Update 3 upvotes 7 months ago

The user transitioned from finasteride to RU58841 and oral minoxidil to maintain hair gains while avoiding systemic DHT suppression. They have not experienced increased shedding or side effects since stopping finasteride and hope RU58841 will preserve their hair.