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Protein Kinase C Epsilon, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

research Protein Kinase C Epsilon, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

10 citations, January 2013 in “Journal of skin cancer”

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells

43 citations, December 2008 in “Molecular biology of the cell”

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin

326 citations, February 2009 in “The American journal of pathology”

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis Through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance

26 citations, July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

research Hair, Cutaneous Homeostasis, and Stem Cell Functions

January 2014 in “Journal of Investigative Dermatology”

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

View more "cd34 a6 double-positive keratinocytes" in research →

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community A reasonably reputable guy claims that he has reversed his hairloss. Could be an interesting read.

16 upvotes 9 years ago

A user shared a blog post by "swissTemples" claiming to have reversed hair loss using a combination of treatments including suppressing PGD2 and increasing PGE2. The user noted that "swissTemples" has been banned from forums, possibly due to conflicts of interest.