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This study found that in a mouse model of psoriasis, depleting CD169⁺ macrophages led to milder symptoms and decreased inflammation, suggesting these macrophages play a crucial role in psoriasis development.

In this study, CD109 overexpression in transgenic mice led to reduced inflammation and improved collagen organization during wound healing without affecting wound closure.

This study found that macrophages near hair follicles contribute to the activation of skin epithelial stem cells in mice, suggesting a novel role for macrophages in regulating hair growth.

This study found that macrophages are crucial for skin regeneration during tissue expansion, as their depletion in rats led to inhibited skin growth and reduced secretion of key growth factors.

This review discusses the role of dermal macrophages in stress-induced hair regeneration and reports no new clinical findings, highlighting the need for further research into macrophage dynamics for potential hair loss therapies.