The study suggests that refractory chronic alopecia areata cases have more infiltrating skinresident memory Tcells, and using a JAK inhibitor may be an effective treatment option.
This review highlights the role of epidermal tissue-resident memory T (T RM) cells in human skin, showing their involvement in immune surveillance and regulation within the epidermis, and suggesting their importance in understanding skin diseases like HIV infection and vitiligo.
36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine”
This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.