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community Breezula - who tried CB0301/Clascoterone from gray marked/pharmas ?

1 upvotes 7 months ago

The conversation discusses using CB0301/Clascoterone as a potential treatment for hair loss, especially for those experiencing side effects from finasteride and dutasteride. The user currently uses oral minoxidil and considers combining it with other treatments like kx826, DHT blocker supplements, and 2% Nizoral shampoo.

community CB-03-01 / Breezula Personal Results

17 upvotes 7 months ago

The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

community RU58841 vs. KX-826 vs. CB-03-01

16 upvotes 3 months ago

RU58841 shows the strongest results despite weaker binding affinity, while KX-826 and CB-03-01 are more expensive and have minimal side effects. RU58841 is considered effective but has potential health risks if ingested; users report positive outcomes with RU58841 and finasteride.

community Clascoterone/ Breezula will it work

5 months ago

Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

community Why are people so negative regarding Clascoterone (Breezula)?

20 upvotes 4 months ago

Clascoterone (Breezula) shows promising hair growth results, but skepticism remains due to past disappointments with new treatments. It may be a good alternative for those who can't tolerate finasteride or dutasteride, and can potentially be combined with them and minoxidil for better results.

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Learn

5 / 801 results

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

Does clascoterone have any side effects? Clascoterone may cause mild skin reactions like redness, itching, and dryness.
Is clascoterone suitable for both men and women? Clascoterone is not approved for hair loss in either sex — the approved product is a 1% acne cream. The scalp version has completed phase III trials in men with sponsor-reported positive results; in women the only data is a company-reported phase II significant in one subgroup, so use is off-label and investigational for both.

learn Overview

learn Climbazol

learn Beclomethasone

learn Behentrimonium cloride

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Research

5 / 1000+ results

research New drugs under investigation for the treatment of alopecias

26 citations , January 2019 in “Expert Opinion on Investigational Drugs”

This review explored the new and emerging treatments for androgenetic alopecia and alopecia areata, finding that JAK inhibitors show promise for alopecia areata, while advancements in stem-cell research may eventually lead to new and improved treatments for androgenetic alopecia.

research Clascoterone: First Approval

27 citations , October 2020 in “Drugs”

This article reviews the development milestones of clascoterone up to its first approval for treating acne vulgaris, reporting no new clinical results for androgenetic alopecia.

New Therapeutics in the Management of Androgenetic Alopecia

research Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique

March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)”

This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.

research Androgenetic Alopecia: An Update of Treatment Options

110 citations , August 2016 in “Drugs”

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

research Experimental and early investigational drugs for androgenetic alopecia

11 citations , July 2017 in “Expert Opinion on Investigational Drugs”

This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.

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