April 2012 in “Cancer Research” In this study, mouse models with EGFR deficiency showed that disrupted hair follicle cycling leads to increased mast cell numbers and inflammation, suggesting EGFR's role in managing hair cycle transitions and preventing folliculitis.
10 citations
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December 2015 in “Experimental dermatology” This study found that in mice, EGFR activation suppresses mitotic regulators like Rcc2 and Stathmin 1, facilitating the transition to catagen in hair follicles.
1 citations
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July 2022 in “Journal of dermatology” This study found that in vivo and in vitro, citric acid metabolism through the CS-CA axis suppressed hair growth and induced inflammation and cell apoptosis in hair follicles, suggesting it as a potential therapeutic target.
October 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that overexpression of the anti-apoptotic protein Bcl-2 in mice disrupted cell death during the hair cycle, impairing hair regeneration by delaying anagen entry and hair growth.
July 2019 in “Journal of Investigative Dermatology” This article previews a Journal of Investigative Dermatology quiz on diagnosing male androgenetic alopecia and offers no new research results.