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This study found that overexpression of an enzyme in transgenic mice led to distorted polyamine levels, resulting in permanent hair loss and female infertility.

This study found that overexpression of the enzyme SSAT in a mouse model significantly reduced prostate tumor size and progression, suggesting it could be a promising strategy against prostate cancer.

This study found that administering the gut bacterium Thauera sp. strain GDN1 to mice significantly reduced their serum androgen levels, indicating gut bacteria may influence androgen metabolism.

This study found that elevated epidermal ODC activity in transgenic mice promotes skin tumor development by recruiting bulge stem cells, rather than through reactive oxygen species generation by polyamine catabolic oxidases.

This study found that oral administration of Thauera sp. strain GDN1 reduced serum androgen levels in male mice by about 50%, suggesting its potential as a probiotic treatment for hyperandrogenism.