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GlossaryCalcitonin Gene-Related Peptide

neuropeptide involved in pain transmission and blood flow regulation

Calcitonin Gene-Related Peptide (CGRP) is a neuropeptide that plays a crucial role in the transmission of pain and the regulation of blood flow. It is often associated with migraine pathophysiology, as elevated levels of CGRP are found during migraine attacks, making it a target for certain migraine treatments.

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research Effects of Guasha on histomorphology of scraped skins and on expression of calcitonin gene-related peptide and substance P in rats

3 citations , August 2018 in “Deleted Journal”

Guasha changed rat skin appearance and blood vessels temporarily without affecting certain nerve proteins or fiber structure.

research 468 Use of calcitonin gene-related peptide monoclonal antibodies in patients with rosacea: An exploratory, comparative case series

May 2023 in “Journal of Investigative Dermatology”

CGRP MAbs treatment for migraines may also improve rosacea symptoms, but more research is needed to confirm its effectiveness and safety.

Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study

research Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study

August 2023 in “Journal of The American Academy of Dermatology”

Some drugs linked to growth hormones may increase the chance of hair loss in women.

research Somatosensory organization and behavior in naked mole‐rats: II. Peripheral structures, innervation, and selective lack of neuropeptides associated with thermoregulation and pain

101 citations , August 2003 in “Journal of comparative neurology”

Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.

research Alcohol extract from Vernonia anthelmintica willd (L.) seed counteracts stress-induced murine hair follicle growth inhibition

6 citations , December 2019 in “BMC Complementary and Alternative Medicine”

Alcohol extract from Vernonia anthelmintica seeds may help treat stress-related hair loss.

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