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    Glossary Calcitonin Gene-Related Peptide

    neuropeptide involved in pain transmission and blood flow regulation

    Calcitonin Gene-Related Peptide (CGRP) is a neuropeptide that plays a crucial role in the transmission of pain and the regulation of blood flow. It is often associated with migraine pathophysiology, as elevated levels of CGRP are found during migraine attacks, making it a target for certain migraine treatments.

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    1. Peripheral patterns of calcitonin‐gene‐related peptide general somatic sensory innervation: Cutaneous and deep terminations The Journal of Comparative Neurology · 1989 · 227 citations
    2. Calcitonin gene‐related peptide (CGRP) may award relative protection from interferon‐γ‐induced collapse of human hair follicle immune privilege Experimental Dermatology · 2011 · 47 citations
    3. Effects of Guasha on histomorphology of scraped skins and on expression of calcitonin gene-related peptide and substance P in rats Deleted Journal · 2018 · 3 citations
    4. 468 Use of calcitonin gene-related peptide monoclonal antibodies in patients with rosacea: An exploratory, comparative case series Journal of Investigative Dermatology · 2023
    5. Medications affecting the insulin-like growth factor 1/growth hormone axis, including teprotumumab, somatostatin analogs, and anti-calcitonin gene-related peptide monoclonal antibodies, are associated with elevated reporting odds of alopecia in women: A pharmacovigilance study Journal of The American Academy of Dermatology · 2023
    6. Adverse event reporting of four anti-Calcitonin gene-related peptide monoclonal antibodies for migraine prevention: a real-world study based on the FDA adverse event reporting system Frontiers in Pharmacology · 2024 · 30 citations
    7. Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin, and Hair Growth Modulation by Neuropeptides Journal of Investigative Dermatology · 2001 · 112 citations
    8. [Peptidergic innervation in the sinus hair follicles of several mammalian species]. PubMed · 1992 · 7 citations
    9. Botulinum toxin effects on biochemical biomarkers related to inflammation-associated head and neck chronic conditions : a systematic review of clinical research Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) · 2025
    10. Somatosensory organization and behavior in naked mole‐rats: II. Peripheral structures, innervation, and selective lack of neuropeptides associated with thermoregulation and pain Journal of comparative neurology · 2003 · 101 citations
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