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This study found that ultraviolet radiation negatively affects hair follicle functions in human scalp skin, and caffeine application may provide some protective effects against this damage.

This study found that ultraviolet radiation causes significant damage to human hair follicles, including increased cell apoptosis and oxidative DNA damage, but this damage may be mitigated by topical caffeine.

This study concluded that a regimen containing functional antioxidants and barrier-enhancing agents reduced hair shedding and increased perceived hair fullness in participants with self-perceived hair thinning over 24 weeks.

This review discusses the potential benefits of using topical caffeine products for treating androgenic alopecia but reports no new clinical findings; the authors highlight caffeine's possible positive effects based on existing studies.

This case report discusses a patient with female androgenetic alopecia and chronic telogen effluvium, emphasizing the importance of follicular unclogging to enhance treatment effectiveness, combining deep cleaning, caffeine application, physical stimulation, and lifestyle changes as an individualized, effective alternative to oral medications.