research Impact of mTORC1 Inhibition on Keratinocyte Proliferation During Skin Tumor Promotion in Wild-Type and BK5.AktWT Mice
Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
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5 / 20 resultsresearch Targeting mTORC1 May Provide Selectivity for Inhibiting Proliferation of Hair Follicle Stem/Progenitor Cells During Tumor Promotion
Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.
research Targeting mTORC1 Suppresses Proliferation of Keratinocyte Stem Cells and Inhibits Skin Tumor Promotion in Mice
Blocking mTORC1 reduces skin tumor growth in mice.
research Constitutive Stat3 Activation Alters Behavior of Hair Follicle Stem and Progenitor Cell Populations
Increased Stat3 activity reduces hair follicle stem cells and boosts other stem/progenitor cells.
research Epidermal Hyperplasia and Oral Carcinoma in Mice Overexpressing the Transcription Factor ATF3 in Basal Epithelial Cells
Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.
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