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research The influence of valproic acid treatment on hair and serum zinc levels and serum biotinidase activity

36 citations , October 2008 in “European journal of paediatric neurology”

This study found that pediatric patients on valproic acid may experience hair loss due to reduced zinc and biotinidase levels within the first 3 months, with zinc depletion continuing to contribute by the 6th month.

Study of Association Between Valproic Acid Levels, Biotinidase Activity, and Hair Loss in Indian Population: A Cross-Sectional Comparative Study

research Study of association between valproic acid levels, biotinidase activity and hair loss in Indian population: A cross-sectional comparative study

September 2025 in “Indian Journal of Psychiatry”

This study found that individuals taking valproate had a higher incidence of hair loss and reported an association between valproate levels, reduced biotinidase activity, and hair loss, compared to a control group.

research The Influence of Valproic Acid and Carbamazepine Treatment on Serum Biotin and Zinc Levels and on Biotinidase Activity

21 citations , June 2011 in “Journal of child neurology”

This study found that while serum zinc levels were lower in children treated with valproic acid or carbamazepine than in healthy controls, zinc, biotin, and biotinidase enzyme activity remained within normal ranges and unaffected by these treatments.

research Clinical, biochemical and mutational findings in biotinidase deficiency among Malaysian population

8 citations , December 2019 in “Molecular genetics and metabolism reports”

This study found that early biochemical screening and molecular confirmation are crucial for distinguishing profound from partial biotinidase deficiency, which supports timely treatment and management in symptomatic children.

research The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid

22 citations , September 2008 in “Brain & development”

In this study on rats, valproic acid was associated with reduced biotinidase enzyme activity and higher alopecia rates, but biotin supplementation did not significantly affect alopecia occurrence.

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Learn

4 / 801 results

learn biotinyl

learn Biotinyl-GHK

learn Biotin

supplement to help with hair texture and quality

How much biotin is too much biotin? The NIH Adequate Intake for adults is 30 mcg of biotin a day, and supplements often contain hundreds of times that; no toxic dose has been identified, but the FDA warns that high-dose biotin can distort blood tests including troponin, so tell your doctor and the lab before any test.
Biotin: the darling of hair products. Biotin may support hair health, but its effectiveness varies and is often overstated.
Biotin, Biotinyl-GHK, biotinoyl-tripeptide-1… are they not the same? Biotin, Biotinyl-GHK, and Biotinoyl-Tripeptide-1 are different compounds with distinct functions.

learn Biotinoyl tripeptide 1

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Community Join

4 / 1000+ results

community Blood Test Recommendations & Brewers Yeast

3 upvotes 1 year ago

The user is considering blood tests to understand their receding hairline and is exploring brewer's yeast for its biotin content. They have been using topical Minoxidil, biotin, collagen, and microneedling, but are avoiding oral Finasteride and Dutasteride.

community Vitamin B5/B6 + Biotin? Any other multivitamins you guys take?

in Product 7 months ago

The conversation is about using Vitamin B5, B6, and Biotin for hair health, with a focus on whether to take these supplements separately when using topical finasteride products. One user dismisses the effectiveness of multivitamins.

community Difference in results between .55mg Fin/2.5mg Min/.5mg Biotin vs 1.1mg Fin/5mg Min1mg Biotin

in Treatment 6 months ago

The conversation discusses the effectiveness and potential side effects of using a minoxidil, finasteride, and biotin combination pill for hair loss, comparing half-dose (0.55mg Fin, 2.5mg Min, 0.5mg Biotin) to full-dose (1.1mg Fin, 5mg Min, 1mg Biotin). The user is considering whether to increase to a full dose after starting with a half dose.

community How biotin benefited you? Could it strengthen hair?

in Product 6 upvotes 1 year ago

Biotin may strengthen existing hair and reduce hair loss, but it doesn't promote new hair growth. Some users report stronger, darker hair, while others see no benefits or experience acne.

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Clinics

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