53 citations
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March 2003 in “Journal of Investigative Dermatology”
This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotin transport component.
This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.
This review discusses the role of biotin in enzyme function and its effects on hair, skin, and nail health, noting that significant improvements are mostly seen in people with biotin deficiency, and reports no new clinical results.
169 citations
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June 2010 in “Molecular & cellular proteomics”
This study suggests that ethylene and lignoceric acid (C24:0) may promote cotton fiber and Arabidopsis root hair growth by activating the pectin biosynthesis network.
4 citations
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January 2015 in “Journal of microbial & biochemical technology”
In this study, the researchers observed that biotin administration in biotin-deficient children with alopecia eliminated certain membrane proteins from their blood, suggesting that biotin might regulate these proteins' expression.
How much biotin is too much biotin?The NIH Adequate Intake for adults is 30 mcg of biotin a day, and supplements often contain hundreds of times that; no toxic dose has been identified, but the FDA warns that high-dose biotin can distort blood tests including troponin, so tell your doctor and the lab before any test.
A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.
People often turn to natural remedies like saw palmetto and rosemary oil for hair loss, but these are not as effective as FDA-approved treatments like finasteride and minoxidil. Some users express concerns about potential side effects of finasteride, while others share positive experiences with it.
A user shared their experience with hair regrowth using supplements like NAC and DIM, and briefly using minoxidil with microneedling. They reported some improvement in hair density, but the community questioned the effectiveness compared to traditional treatments like finasteride.
A user tried various hair growth treatments, including drinking topical minoxidil, using oral minoxidil and finasteride, and applying GHK-Cu, growth hormone peptides, and liposomal sulforaphane. They experienced thicker hair, while others discussed the risks and benefits of these methods.
A young person is experiencing aggressive hair loss and not responding well to minoxidil and finasteride. Suggestions include trying dutasteride, hair systems, lifestyle changes, or considering a wig.