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research In-silico studies in herbal drugs: A review

April 2018 in “Journal of Ayurvedic and herbal medicine”

This study highlights the role of bioinformatics and in-silico studies for identifying drug targets, specifically in herbal drugs, using software and modern techniques to analyze data and model disease pathways before later-stage in vivo and in vitro testing.

research Identification of a recurrent nonsense mutation in HR gene responsible for atrichia with papular lesions in two Kashmiri families

3 citations , February 2020 in “The journal of gene medicine”

This study found a recurrent nonsense mutation in the HR gene linked to atrichia with papular lesions in two Kashmiri families, suggesting whole exome sequencing as an efficient method for diagnosis and genetic counseling.

research Discovery Potential Hub Genes and Pathways in Keloid Fibroblast Development Based on Bioinformatics Analysis

January 2025 in “International Journal of Genomics”

This study identified three hub genes—BMP4, POSTN, and WNT5A—that are closely associated with keloid fibroblast hyperplasia, suggesting they may serve as potential biomarkers for inhibiting this condition. Further research is necessary to fully understand their roles in keloid development.

research Exploring the Potential Role of Hydroxytyrosol in Androgenetic Alopecia: An Integrated Bioinformatics and Molecular Simulation Study

May 2026 in “International Journal of Molecular Sciences”

This study suggests that hydroxytyrosol may influence inflammation and oxidative stress pathways in androgenetic alopecia, particularly through interaction with the PTGS2 gene, warranting further experimental validation.

research A novel predictive model for the recurrence of pediatric alopecia areata by bioinformatics analysis and a single-center prospective study

3 citations , June 2023 in “Frontiers in Medicine”

This study constructed a model using serum levels of BMP2, CD8A, PRF1, and XCL1 as a non-invasive biomarker to accurately predict recurrence in patients with alopecia areata.

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community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

Clinics

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Hair Loss TreatmentsTrichology
Institute of Trichology StudiesFort Worth, TX · US

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