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research Are Women with Polycystic Ovary Syndrome at Increased Risk of Alzheimer Disease? Lessons from Insulin Resistance, Tryptophan and Gonadotropin Disturbances and Their Link with Amyloid-Beta Aggregation

4 citations , July 2024 in “Biomolecules”

This review suggests systemic changes in polycystic ovary syndrome may increase the risk of neurodegeneration, potentially linking it to Alzheimer's disease through common pathways affecting tryptophan metabolism.

research Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits

January 2024 in “International journal of molecular sciences”

This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.

research Innovative Reports on the Effects of Anabolic Androgenic Steroid Abuse—How to Lose Your Mind for the Love of Sport

August 2023 in “Medicina-lithuania”

This review discusses the degenerative effects of anabolic-androgenic steroids on the nervous system and reports no new experimental results, aiming to increase public awareness of their health risks.

Cerebronal® Food Supplement Improves Status of Markers of Dementia and Regeneration

research Cerebronal® food supplement improve status of markers ofdementia and regeneration

September 2025 in “Dietary Supplements and Nutraceuticals”

In this study, the authors reported that Cerebronal® supplementation for three to six months may modulate certain biomarkers associated with neurodegeneration and brain repair in individuals with memory problems.

research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning

January 2017 in “Brazilian Journal of Pharmaceutical Sciences”

This study identified neprilysin as a potential target of the pharmacological agent arteannuin, which may guide future research into its clinical applications, although experimental verification is needed.

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community Bruteforcing alopecia or the new advent of science progress

22 upvotes 1 year ago

Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.

community Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate.

in Research/Science 9 upvotes 3 years ago

Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.

community Beta blocker and diuretic to manage oral minoxidil sides?

3 upvotes 4 years ago

community Anyone take Beta Blocker and notice hair thinning?

4 upvotes 5 years ago

Beta blockers may cause hair thinning as a side effect. The user is concerned about this and seeks others' experiences with hair loss while using beta blockers.

community Trying to remember the name of a supplement someone on here told me about.. nvm I just remembered beta sitosterol.

4 upvotes 8 years ago

Beta sitosterol is mentioned as a supplement for hair loss. Minoxidil, finasteride, and RU58841 are also discussed as treatments.

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What is Thymosin Beta 4, and why is it being researched in relation to hair follicle function and regeneration? Thymosin Beta 4 is a peptide being researched for its potential to enhance hair follicle regeneration.
How is Thymosin Beta 4 typically incorporated into experimental or advanced hair growth products? Thymosin Beta 4 is not an ingredient in any approved or regulated hair-loss product — it is an unapproved research peptide (sold online as TB-500). Published hair studies are in rats and mice only, from one research group; there are no human trials, and the same literature reports it can promote tumour growth.
What role does Thymosin Beta 4 play in scalp biology compared to traditional hair loss treatments? Thymosin Beta 4 may enhance scalp biology but lacks extensive clinical validation compared to traditional treatments.
All 5 questions on Thymosin Beta 4 →

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