Beta sitsterol
Research
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research Critical Analysis on Characterization, Systemic Effect, and Therapeutic Potential of Beta-Sitosterol: A Plant-Derived Orphan Phytosterol
This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.
research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study
This study reports that using molecular docking methods, beta-sitosterol and stigmasterol from Serenoa repens were identified as potential natural inhibitors of the 5AR1 enzyme, which could serve as novel treatments for androgenetic alopecia based on their inhibitory action observed in a laboratory setting.
research Formulation and Evaluation of Beta-Sitosterol Enriched Herbal Scalp Serum
This study reported the development of a scalp serum containing Beta-Sitosterol and nutrient-rich oils, showing stable physicochemical properties, suggesting potential for promoting hair growth and scalp health, though further clinical testing in humans is needed to confirm effectiveness.
research Process Validation of Beta-Sitosterol Hair Gel Formulation and Evaluation of 5 Alpha Reductase Inhibition In Vitro for the Treatment of Androgenetic Alopecia
In this study, researchers formulated a topical gel containing β-sitosterol for alopecia treatment and found it demonstrated good 5 alpha reductase inhibitory activity in vitro, comparable to a commercial product, indicating its potential for further antiandrogenic activity investigation.
research Preparation and Characterization of Beta-Sitosterol-Loaded Nanostructured Lipid Carriers for Butter Enrichment
This study found that betasitosterol-loaded nanostructured lipid carriers, when added to butter, improved its nutritional profile and antioxidant properties, maintaining stability over a three-month storage period.
research Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid, and Carnitine-Containing Compound in Prostate and Hair Follicle Cell-Based Assays
In laboratory tests, this study found that a novel natural composition targeting 5-alpha reductase and inflammatory pathways reduced disease-related markers in androgenetic alopecia and benign prostatic hyperplasia more effectively than finasteride.
research Development and Characterization of Phyto-Vesicles of Beta-Sitosterol for the Treatment of Androgenetic Alopecia
This study found that phyto-vesicles of ß-sitosterol showed better absorption and improved activity for treating androgenetic alopecia in rats compared to the compound and its complex.
research Exploring the Inhibitory Potential of Phytosterols Beta-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach
This study found that the phytosterols β-sitosterol, stigmasterol, and campesterol have low-to-negligible inhibitory activity against steroidal 5α-reductase type 2 compared to the synthetic inhibitor dutasteride, with β-sitosterol showing the highest activity among the tested phytosterols.
research Enhanced Skin Permeation and Controlled Release of Beta-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia
This study found that cubosomes combined with dissolving microneedles enhanced transdermal penetration and hair growth efficacy of beta-sitosterol for treating alopecia.
research Microneedle Mediated Transdermal Delivery of Beta-Sitosterol Loaded Nanostructured Lipid Nanoparticles for Androgenic Alopecia
This study found that a transdermal drug delivery system using nanostructured lipid carriers and polymeric microneedles for β-sitosterol significantly enhanced hair growth in testosterone-induced alopecia rats, suggesting potential for treating androgenic alopecia.
research Standardization of Amarantha Hair Oil with Special Reference to Identification of β-Sitosterol as Major Component Having 5α-Reductase Inhibitory Activity/Hair Growth Promoting Activity
This study observed that Amarantha hair oil contains β-sitosterol, which is suggested to promote hair growth.
research A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia
This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
This study reports that newly synthesized steroidal trienones exhibit higher 5α-reductase inhibitory activity than dienones in various biological models, suggesting potential use in treating androgen-dependent diseases.
research Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production
This source highlights that while plant sterols show potential benefits and applications in various industries, significant research gaps, including their complex structures and mechanisms, hinder their broader use, emphasizing the need for innovative sources and sustainable methods for their study.
research Identification of Hair Growth Promoting Components in the Kernels of Prunus Mira Koehne and Their Mechanism of Action
This study found that components in the kernel of Prunus mira Koehne, such as vitamin E and β-sitosterol, may promote hair growth in mice, possibly involving the Wnt/β-catenin signaling pathway.
research How to Defeat Male Pattern Alopecia in a Womanizer Who Abuses Libido Boosters
This article discusses the familiarity of identifying male androgenetic alopecia but presents no new research findings.
research Standardization of Eclipta Alba by HPTLC, HPLC, and AAS
This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
research Phytotherapy in Trichology: A Review
This review highlights that natural DHT blockers like saw palmetto and pumpkin seed oil show promise in managing androgenetic alopecia, though clinical data varies, and further research is needed to confirm their efficacy and safety in comparison to conventional pharmaceuticals.
research Referee Report: Exploring the Use of Phytotherapy in Benign Prostatic Hyperplasia (BPH): A Systematic Review
Plant-based treatments may help reduce BPH symptoms, but more research is needed.
research Identification and In-Silico Analysis of Phytochemicals from Phyla Nodiflora: Potential Bioactive Compounds for Therapeutic Applications
This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.