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2 / 2 resultslearn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
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5 / 1000+ resultsresearch 6 Current concepts of polycystic ovary syndrome
PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
![Insulin resistance and β-cell dysfunction and the relationship with cardio-metabolic disorders among women with polycystic ovary syndrome](/images/research/e613d0a0-1a68-4114-9237-cdaf6f39e6b0/small/13578.jpg)
research Insulin resistance and β-cell dysfunction and the relationship with cardio-metabolic disorders among women with polycystic ovary syndrome
Women with PCOS have more insulin resistance and are more likely to have heart-related health issues, with insulin resistance being a bigger factor than β-cell problems.
research Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice
Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.
![Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome](/images/research/eaccf670-c256-4e96-88ce-a6080136d25b/small/12941.jpg)
research Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome
Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
![Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review](/images/research/12e9d063-23da-4467-b91b-61c3a7af1012/small/19170.jpg)
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
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5 / 96 resultscommunity An argument for why we should take topical Dutasteride seriously
Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.
community TGF-Beta. Good or Bad? Help for treatment investment
TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.
community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications
The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.
community Tretinoin potentially can make hair loss worse ?
Tretinoin may worsen hair loss by inducing premature hair follicle regression. It can be used with minoxidil to increase absorption but should not be used alone.
community We don't talk about vitamin E enough
A user shared that taking vitamin E, specifically tocotrienols, seemed to reduce their hair shedding, and they are also using finasteride, minoxidil, and derma rolling for hair loss. Another user cautioned against high doses of vitamin E due to potential health risks.