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research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds

6 citations, August 2004 in “Journal of Chemical Information and Computer Sciences”

The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.

research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1

12 citations, June 2001 in “Bioorganic & Medicinal Chemistry”

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2

9 citations, November 2004 in “Bioorganic & Medicinal Chemistry Letters”

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1

28 citations, September 2000 in “Journal of Medicinal Chemistry”

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives

233 citations, November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

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community RU58841 powder from lab supplier tested at free drug testing service

in Treatments 207 upvotes 11 months ago

RU58841 powder from a lab supplier was tested at a free drug testing service. The discussion includes using Minoxidil and finasteride for hair loss treatment.

community What to do if fin is still not working after 2.5 years

in Finasteride/Dutasteride 22 upvotes 2 months ago

The user is experiencing increased hair loss despite using finasteride and oral minoxidil and is hesitant to switch to dutasteride due to side effects and family planning concerns. Alternatives suggested include dutasteride, microneedling, and addressing stress or nutrient deficiencies.

community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

in Transgender 611 upvotes 9 months ago

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

community How to reduce cortisol (stress hormone) naturally?

in Chat 37 upvotes 3 years ago

The conversation discusses natural ways to reduce cortisol, such as avoiding caffeine, getting proper sleep, syncing with the sun, walking in nature, breathing exercises, increasing calories, and not doing keto. Magnesium supplements are recommended for stress reduction.

community Do 'do it yourself' topical fin really work?

in Treatment 1 upvotes 2 weeks ago

DIY topical finasteride mixed with minoxidil is used due to the unavailability of pharmacy-grade options in Sweden. The user reports positive results after three months, with improved hair growth at the temples and vertex.

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