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The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

The exact causes of baldness are not fully understood, limiting treatment options.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Certain Dibenzo derivatives may help treat prostate cancer.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

Analog 23 is a promising compound for prostate cancer treatment.

Human hair follicles can assess carcinogen metabolism and imidazole compounds might be effective anticarcinogens.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.

TCDD disrupts skin stem cells, causing skin issues like chloracne.