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CYP21A2 Genotypes Do Not Predict the Severity of Hyperandrogenic Manifestations in the Nonclassical Form of Congenital Adrenal Hyperplasia

research CYP21A2 Genotypes do not Predict the Severity of Hyperandrogenic Manifestations in the Nonclassical Form of Congenital Adrenal Hyperplasia

14 citations , January 2013 in “Hormone and Metabolic Research”

This study found that in patients with nonclassical 21-hydroxylase deficiency, genotypes do not reliably predict the severity of hyperandrogenic symptoms, suggesting other genetic factors may influence the phenotype.

Receiver Operating Characteristic Analysis of the Performance of Basal Serum Hormone Profiles for the Diagnosis of Polycystic Ovary Syndrome in Epidemiological Studies

research Receiver operating characteristic analysis of the performance of basal serum hormone profiles for the diagnosis of polycystic ovary syndrome in epidemiological studies

66 citations , November 2001 in “European journal of endocrinology”

This study suggests that decreased SHBG levels and increased FAI, free testosterone, and DHEAS concentrations are effective in diagnosing PCOS in epidemiological studies of women of reproductive age.

The Influence of Non-Esterified Fatty Acids on Ovarian Androgen Production in IVF – Preliminary Results

research The influence of non-esterified fatty acids (NEFA) on the ovarian production of androgens in a context of in vitro fertilisation (IVF) – preliminary results

August 2013 in “Fertility and Sterility”

This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.

research Differential Diagnosis of Hyperandrogenism in Women with Polycystic Ovary Syndrome

35 citations , March 2012 in “Experimental and Clinical Endocrinology & Diabetes”

This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.

research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor

17 citations , October 2006 in “Molecular and Cellular Endocrinology”

This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.

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community Blood test results and alternatives to oral finasteride

in Treatment 7 upvotes 1 year ago

The user experienced erectile dysfunction from oral finasteride and is considering alternatives like topical high-dose finasteride, RU58841, topical Latanoprost, and oral Minoxidil. Blood tests showed changes in testosterone and DHT levels, and the endocrinologist advised stopping finasteride.

community Cardio for more than 60 minutes reduces DHT levels and improve hair growth

in Research/Science 126 upvotes 1 year ago

Long aerobic exercise (over 60 minutes) can reduce DHT levels and improve hair health. Some users discuss using Tadalafil (Cialis) to further reduce DHT after exercise, while others mention using treatments like Minoxidil, Finasteride, and RU58841 for hair growth.

community Does DHT give you a leaner face?

in Finasteride/Dutasteride 44 upvotes 1 year ago

Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.

community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Could creatine trigger faster hairloss?

29 upvotes 2 years ago

Creatine is reported by many to increase hair loss, though no scientific evidence supports this. Some use finasteride and minoxidil to manage hair loss, while others avoid creatine due to personal experiences.

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