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This study found that in patients with nonclassical 21-hydroxylase deficiency, genotypes do not reliably predict the severity of hyperandrogenic symptoms, suggesting other genetic factors may influence the phenotype.

This study suggests that decreased SHBG levels and increased FAI, free testosterone, and DHEAS concentrations are effective in diagnosing PCOS in epidemiological studies of women of reproductive age.

This study found that women with PCOS have higher follicular fluid levels of testosterone and IL-6, despite similar NEFA levels to non-PCOS women, suggesting increased lipotoxicity impact on androgenesis in PCOS.

This article discusses various causes of hyperandrogenism in women and highlights diagnostic considerations for conditions such as PCOS, NCCAH, Cushing's disease, and androgen-secreting tumors, without reporting new clinical results.

This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.

This study found that canrenone significantly reduced hair growth and decreased certain androgen levels in women with idiopathic post-puberal hirsutism, suggesting potential effectiveness as a treatment.

This study found that finasteride effectively prevented testosterone-induced kidney stone formation in renal tubular cells by reducing COM crystal adhesion and crystallization.

In this study, treatments combining betamethasone and anovulatory steroids significantly reduced testosterone production in women with hirsutism, with many reporting improved hirsutism and acne, although clinical benefit did not consistently correlate with testosterone reduction.

This study found a significant association between patients' sex of rearing and external genitalia in those with gonadal dysgenesis, while noting lower testosterone levels compared to controls.

This case study reports that hormonal imbalances in a young boy with precocious pseudopuberty returned to normal after the removal of a testicular interstitial cell tumor, with normal spontaneous puberty following.

This study found that low doses of leuprolide effectively suppressed serum estradiol and LH response, while higher doses were needed to suppress testosterone and reduce hair growth in hirsute women.

This study reported that ketoconazole may effectively normalize menstruation and reduce testosterone and hair growth in women with ovarian hyperandrogenism, though its safety needs further evaluation.

This study found that spironolactone may improve acne and some ovarian functions in patients with irregular menstrual periods and androgenic symptoms, while causing few side effects.

This study concluded that spironolactone may be an effective therapy for a subgroup of hirsute patients, as it reduced plasma testosterone and improved certain hair growth measures.

Among females with nonclassical 21-hydroxylase deficiency, this study found that low-dose glucocorticoid treatment improved fertility outcomes by increasing pregnancy and live birth rates while reducing miscarriage rates.

This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.

This study found that salivary testosterone levels were significantly lower in oligospermic and azoospermic men compared to normal men, suggesting its potential use in assessing male androgen status.

In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.

This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.

In this animal study, finasteride was found to significantly lower cortisol and increase testosterone levels in female rats, indicating its broader impact on endocrine regulation by altering adrenal and gonadal hormones.

This study found that administering an alcoholic extract of Mentha spicata leaves significantly reduced testosterone levels and aggressive behavior in female rats with elevated testosterone, suggesting its potential protective role against such symptoms.

Blood AMH levels are higher in women with PCOS than in those with other similar conditions.

This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.

This study found that administering testosterone increased the expression of sexual behavior and elevated serum testosterone and DHT levels in female capuchin monkeys, hinting at potential insights into testosterone use and its risks in humans.

This study found that nonobese women with idiopathic hirsutism had higher fibrinogen levels and lower nitrite/nitrate concentrations compared to controls, similar to those with PCOS.

In this study, hyperandrogenemia in young women with polycystic ovary syndrome was linked to higher blood pressure, independent of factors like age, insulin resistance, obesity, or dyslipidemia.

Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.

This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.

This study examined serum PSA levels in women with androgenetic alopecia to evaluate their potential as a marker for androgen effects on target organs.

This review evaluates current research on how hormonal changes due to aging impact voice quality, concluding the vocal cords are sensitive to hormonal fluctuations throughout life but reports no new clinical results.