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      research Common Genetic Hair Shaft Abnormalities May Be Visualized by Light and Electron Microscope

      January 2019 in “Global Dermatology”
      The document discussed genetic hair shaft abnormalities that could be observed using light and electron microscopes. It highlighted conditions such as atopy, where hair breakage occurred due to defective cornification, and monilethrix, an autosomal dominant disorder characterized by fragile, brittle hair with elliptical nodes and constrictions. While scalp hair in adults tended to improve, bamboo defects in eyebrow and body hair could persist. Mutations in genes encoding K83 and Desmoglein were identified, with the scalp usually being the primary area affected, though more extensive cases could involve eyebrows, eyelashes, and nails.

      research MULTIPLE DEFECTS OF THE HAIR SHAFT IN NETHERTON'S DISEASE.

      58 citations , November 1969 in “British Journal of Dermatology”
      Two patients with ichthyosis linearis circumflexa, a skin condition associated with a syndrome similar to Netherton's disease, exhibited multiple hair shaft defects. These defects included variations in hair thickness, trichorrhexis nodosa, bamboo hairs, and various cup and ball deformities. The study also described the histological features of the hair follicles and explored the potential significance of an associated aminoaciduria.

      research Recurrent bacterial vaginosis and Netherton's syndrome

      4 citations , March 1999 in “International Journal of STD & AIDS”
      Netherton's syndrome, also known as 'bamboo hair' syndrome, was a rare disorder characterized by ichthyosiform dermatosis and distinctive hair shaft defects. It was commonly associated with atopy and recurrent infections, particularly affecting the skin. The document reported a case of a female patient with Netherton's syndrome who experienced severe recurrent bacterial vaginosis, highlighting the syndrome's potential impact on recurrent infections beyond the skin.

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