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This study identified Azithromycin and Roxithromycin as novel senolytic antibiotics that effectively target and reduce senescent human fibroblast cells.

This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.

This study concluded that a sequential regimen of prednisolone and cyclophosphamide, followed by low-dose prednisolone and azathioprine, achieved favorable results in most patients with diffuse proliferative and/or membranous lupus nephritis without significant toxicities.