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research Overnight loss of pigmented hair in autoimmune autonomic neuropathy treated with IVIg

2 citations , September 2019 in “Neurology Neuroimmunology & Neuroinflammation”

This case report describes a patient with autoimmune autonomic neuropathy associated with high-titer gAChR antibodies who developed selective pigmented hair loss during IV immunoglobulin treatment.

research The autoimmune basis of alopecia areata: A comprehensive review

162 citations , October 2014 in “Autoimmunity reviews”

This review discusses alopecia areata, highlighting its autoimmune aspects, environmental triggers, and current treatment options, but reports no new clinical results; recent studies suggest JAK pathway intervention may offer therapeutic potential.

research Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history

January 2007 in “Yearbook of Dermatology and Dermatologic Surgery”

Certain types of alopecia areata are linked to allergies, autoimmune diseases, and family history.

research Alopecia Areata in Children

August 2009 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)”

This article reviews the multifactorial etiology and treatment options for alopecia in children, including potential genetic and autoimmune contributions, but provides no new clinical findings.

research THE PATHOGENESIS OF ALOPECIA AREATA

89 citations , October 1996 in “Dermatologic Clinics”

This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Cetirizine

Could cetirizine help control autoimmune triggers in alopecia areata? No published trial has tested cetirizine in alopecia areata; one registered trial has not reported results. Small trials in pattern hair loss report modest benefit, so any use for alopecia areata is off-label and unproven.

learn Tofacitinib

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

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community Hair loss after COVID or vaccination isn’t “made up” but it’s also not what TikTok makes it sound like

2 upvotes 8 months ago

COVID and COVID vaccination can trigger hair loss, primarily telogen effluvium, due to stress and immune system activation. Proper diagnosis and addressing factors like nutrition and stress are crucial for recovery.

community Losing a ton consistently after 8 months dut please help me I don’t know what to do anymore, nothing works

in Chat 76 upvotes 1 year ago

A 20-year-old is experiencing hair loss despite using dutasteride and oral minoxidil. Suggestions include consulting a specialist, considering RU58841, and checking for other conditions and vitamin deficiencies.

community Hi-c5 protein, explains why the mechanical tension theory may be correct.

22 upvotes 1 month ago

Hair loss may be influenced by mechanical tension and inflammation, with the hi-c5 protein amplifying androgen effects, leading to follicle miniaturization. Treatments like finasteride, minoxidil, and scalp massages are suggested to manage hair loss.

community Before and after of 20 months of fin and min

in Progress Pictures 125 upvotes 7 months ago

The user experienced worsening hair thinning despite using finasteride, minoxidil, and ketoconazole shampoo, and switched to dutasteride five months ago. They are considering adding tretinoin and microneedling to their routine for better results.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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