research Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway
Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
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5 / 407 results research Metformin Protects Against Gentamicin-Induced Hair Cell Death In Vitro But Not Ototoxicity In Vivo
Metformin protects hair cells in lab tests but not in live animals.
research Molecular Basis of Hair Cell Loss
The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
research CFTR Potentiator Ivacaftor Protects Against Noise-Induced Hair Cell Loss by Increasing Nrf2 and Reducing Oxidative Stress
Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
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5 / 7 resultscommunity I bought a Dermastamp instead of a roller and it's weird to hear it crunch into my scalp
A user describes using a Dermastamp for microneedling their scalp, noting a crunching sound when pressing it firmly. Another user suggests the crunching might be from breaking up scalp calcification.
community How does hair loss and recovery work?
Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.
community TWIST-1 and the cure: Is it really that easy?
TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.
community Before/After 1 day topical minoxidil. Anyone else notice it gives you wrinkles and bags under your eyes?
This conversation discussed the side effects of Minoxidil for hair loss, with users sharing their experiences. Treatments such as Retinol and Tretinoin were suggested alongside topical or oral Minoxidil to reduce any negative impacts.
community 23M (yes 23, I'm not kidding), ~6 month progress. I'm on the Big 4 + Vitamin Supplement.
A 23-year-old male shared his 6-month hair loss progress using Minoxidil, Finasteride, Ketoconazole shampoo, microneedling, and vitamin supplements. He noticed hair loss at 19, which accelerated during the pandemic.