1 citations
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July 2022 in “Clinical and Experimental Dermatology” This study suggests that arginine and cysteine deficiency is not present in women with chronic telogen effluvium, indicating that amino acid supplementation may be unnecessary in nutrient-replete populations.
August 2022 in “Clinical and Experimental Dermatology” This study found that serum cysteine levels were not lower in patients with chronic telogen effluvium and did not correlate with hair loss severity.
This study found that androgenetic alopecia patients exhibited impaired arginine metabolism in balding hair follicles, suggesting that arginine supplementation may help preserve hair growth by counteracting mTOR signaling pathway disruption and offering potential as a treatment strategy.
35 citations
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August 2010 in “The American journal of pathology” This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.
15 citations
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August 1991 in “American Journal of Medical Genetics” This study observed that a low-protein, arginine-supplemented diet improved the abnormal hair appearance in untreated patients with argininosuccinic aciduria.