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research Intermolecular NH2-/Carboxyl-Terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity

227 citations, January 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

research 5α-Reduced Glucocorticoids: A Story of Natural Selection

46 citations, September 2011 in “Journal of Endocrinology”

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

research Design and Synthesis of Novel Androgen Receptor Antagonists with Sterically Bulky Icosahedral Carboranes

45 citations, August 2005 in “Bioorganic & medicinal chemistry”

New compounds with carborane showed anti-androgen effects similar to flutamide.

research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme

5 citations, January 2022 in “Clinical cancer investigation journal”

Certain Dibenzo derivatives may help treat prostate cancer.

research Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp

100 citations, September 1999 in “British Journal of Dermatology”

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

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community 50 days on 10% minox .1%fin &biotin compound

in Progress Pictures 32 upvotes 7 months ago

A user shared progress pictures after 50 days of using a compound with 10% minoxidil, 0.1% finasteride, and biotin, expressing satisfaction with the results. Another user commented positively on the progress.

community Why didn’t Prince William hop on fin/min?

in Finasteride/Dutasteride 718 upvotes 1 year ago

Hair loss discussion explores why Prince William didn't use treatments like finasteride or minoxidil. Reasons include indifference to appearance, potential side effects, and royal responsibilities.

community 6 months on oral minox with no result

in Minoxidil 10 upvotes 2 years ago

A user who had taken oral minoxidil for 6 months without seeing any results and the advice given in response, which included trying microneedling in combination with topical minoxidil, as well as seeking a dermatologist's opinion.