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Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Certain Dibenzo derivatives may help treat prostate cancer.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Smart biomaterials that guide tissue repair are key for future medical treatments.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

The PRP-like cosmetic product with postbiotics effectively treats hair loss in Alopecia areata.

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

Skin stem cells in hair follicles are important for touch sensation.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Analog 23 is a promising compound for prostate cancer treatment.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.